Melting point 

33-37°C

alpha 

32 º

Boiling point 

483.46°C (rough estimate)

density 

1.0406 (rough estimate)

refractive index 

1.4700 (estimate)

storage temp. 

2-8°C

solubility 

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.8 mg/mL

form 

powder

color 

white to light yellow

Water Solubility 

664ug/L(37 ºC)

InChIKey

JKWKMORAXJQQSR-MOPIKTETSA-N

CAS DataBase Reference

Hazard Codes 

Risk Statements 

Safety Statements 

WGK Germany 

RTECS 

KG7967000

HS Code 

2937290000

Toxicity

LD50 intraperitoneal in mouse: > 566mg/kg

Chemical Properties

White or almost white, crystalline powder.

Originator

Deca-Durabolin,Organon,US,1962

Uses

Nandrolone Decanoate is an anabolic steroid.
Nandrolone decanoate is used in the treatment of osteoporosis in postmenopausal women.
Nandrolone Decanoate is also used for some aplastic anemias.

Manufacturing Process

1 gram of 19-nortestosterone is dissolved in 3 ml of dry pyridine, after which the resulting solution is cooled to -20°C.
A solution of 1.0 gram of decanoic acid chloride in 3 ml of dry benzene is added to the cooled solution.
The mixture is maintained at -15°C for 16 hours and then poured into ice water.
The aqueous liquid is extracted with benzene, the benzene solution is washed with respectively 1 N sodium hydroxide solution, 2 N hydrochloric acid and with water until neutral reaction.
Then the solution is dried on sodium sulfate, filtered, and evaporated to dryness.
The residue, 1.63 grams is dissolved in hexane, this solution is filtered over 30 grams of neutral aluminum oxide, and evaporated to dryness.
On paper chromatographic investigation it turned out that the obtained 19- nortestosterone 17-decanoate which at room temperature is an oil consists of a single compound, according to US Patent 2,998,423.

Brand name

Durabolin (Organon);Abolon;Activin;Anabolin la 100;Anador;Anadur;Analone-50;Androlone d 100;Androlone d 50;Decabolin;Deca-durabolin decanoate;Deca-noralone;Docabolin;Fherbolico;Fortabolin;Hybolin-decanoate;Iebolan;Kabolin;Keratyl;Methybol-depot;Nandrolone decanoate; Nordecon; Stenabolin;Sterobolin;Turinabol-depot.

Therapeutic Function

Anabolic

World Health Organization (WHO)

Nandrolone decanoate, an anabolic steroid, was introduced in 1962.
In 1982, low dosage preparations were prohibited in Bangladesh due to inadmissible promotion of products containing anabolic steroids for malnourished children. Higher dosage preparations of nandrolone decanoate remain available in many countries, including Bangladesh, for several highly specific but limited indications that apply to patients with chronic debilitating and emaciating diseases, particularly associated with neoplasia and some types of aplastic anaemia.

General Description

Nandrolone decanoate,17β-hydroxyestr-4-en-3-one 17-decanoate, has been used inthe management of certain anemias, but the availability oferythropoietin has greatly reduced this use.

Safety Profile

Experimental reproductiveeffects.
When heated to decomposition it emits acridsmoke and irritating fumes.

Veterinary Drugs and Treatments

The principle use of nandrolone in veterinary medicine has been to stimulate erythropoiesis in patients with certain anemias (e.g., secondary to renal failure, aplastic anemias). It has also been suggested for use as an appetite stimulant.

Raw materials