 
		 
| Product Name: | Ethisterone | 
|---|---|
| Synonyms: | Prone ETHISTERONE | 
| CAS: | 434-03-7 | 
| MF: | C21H28O2 | 
| MW: | 312.45 | 
| EINECS: | 207-096-5 | 
| Product Categories: | Steroids; | 
| Mol File: | 434-03-7.mol | 
 
	| Ethisterone Chemical Properties | |
|---|---|
| Melting point | 263-269 °C(lit.) | 
| alpha | D23 +23.8° (dioxane); D25 -32.0° (pyridine) | 
| Boiling point | 392.36°C (rough estimate) | 
| density | 1.0697 (rough estimate) | 
| refractive index | 33 ° (C=1, Pyridine) | 
| storage temp. | -20°C Freezer | 
| pka | 13.10±0.60(Predicted) | 
| form | neat | 
| Water Solubility | soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C). | 
| Merck | 14,3741 | 
| BRN | 1889895 | 
| InChIKey | CHNXZKVNWQUJIB-CEGNMAFCSA-N | 
| CAS DataBase Reference | 434-03-7 | 
| NIST Chemistry Reference | Ethisterone(434-03-7) | 
| Safety Information | |
|---|---|
| Hazard Codes | Xn,T | 
| Risk Statements | 40-48-61 | 
| Safety Statements | 22-24/25-45-53 | 
| RIDADR | UN 2811 | 
| WGK Germany | 3 | 
| RTECS | TU5570250 | 
| HS Code | 29372390 | 
| Ethisterone Usage And Synthesis | |
|---|---|
| Chemical Properties | Off-White Powder | 
| Originator | Lutocyclin,Ciba | 
| Uses | Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone | 
| Definition | ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group.  | 
| Manufacturing Process | 0.5 part of δ5:6-17-ethinyl-androstendiol-(3:17) is dissolved in 10 parts of dry acetone, the solution is mixed with a solution of 1 part of tertiary aluminum butylate in 40 parts of absolute toluene and the whole is heated to boiling in a reflux apparatus for 21 hours.  | 
| Therapeutic Function | Progestin | 
| Ethisterone Preparation Products And Raw materials | |
|---|---|
| Raw materials | Dehydroepiandrosterone | 

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