JS-BIOLOGY
Ethisterone
Location>Home > Products > Steroid/Hormone Raw Materials
Ethisterone

 图片3.png

Product Name:

Ethisterone

Synonyms:

Prone
Pranone
Pregnin
NSC-9565
Prolutol
Prodoxan
Produxan
Colutoid
Ethinone
Gestoral
Trosinon
prolutonc
Progestab
Prodroxan
primolutc
Trosinone
Ora-Lutin
Lutocylol
Nalutoral
Lutocyclin
Lutocyclol
Primolut C
Nugestoral
Proluton C
progestinp
Progestoral
Progestin P
lutidonoral
 Aethisteron

ETHISTERONE
Lutidon Oral
Progestolets
Syngestrotabs
lucorteumoral
Ethisterone 0
Aethisteronum
ETHISTERONE(P)
Pregneninolone
Lucorteum Oral
Ethisterone,98%
ETHISTERONE(RG)
ETHYNYLTESTOSTERONE
ETHINYL TESTOSTERONE
ETHYNYLANDROSTENOLONE
ANHYDROXYPROGESTERONE
ETHISTERONE(RG)(CALL)
17-Ethinyltestosterone
17A-ETHYNYLTESTOSTERONE
17α-ethynyltestosterone
Testosterone, 17-ethynyl-
ANHYDROHYDROXYPROGESTERONE
4,17A-PREGNEN-17B-OL-20-YNE
17ALPHA-ETHYNYLTESTOSTERONE
17-alpha-ethinyltestosterone
ETHISTERONE WHO(CRM STANDARD)
ETHISTERONE EPE(CRM STANDARD)
17-Hydroxypregn-4-en-zoyn-3-one
17-Hydroxypregn-4-en-20-yn-3-one
(17-alpha)-pregn-4-en-20-yn-3-on
4,17a-pregnen-17b-ol-20-yn-3-one
17a-Hydroxypregn-4-en-20-yn-3-one
17A-ETHYNYL-4-ANDROSTEN-17B-OL-3-ONE
17b-hydroxy-4,17a-pregnen-20-yn-3-one
4,17ALPHA-PREGNEN-17BETA-OL-20-YN-3-ONE
(17α)-17-hydroxy-pregn-4-en-20-yn-3-one
17a-ethynyl-17b-hydroxy-4-androsten-3-one
17-hydroxy-17-alpha-pregn-4-en-20-yn-3-on
17-Hydroxy-17-alpha-pregn-4-en-20-yn-3-one
17-Ethynyl-17beta-hydroxyandrost-4-en-3-one
17alpha-Pregn-4-en-20-yn-3-one, 17-hydroxy-
17BETA-HYDROXY-4,17ALPHA-PREGNEN-20-YN-3-ONE
4-ANDROSTEN-17-ALPHA-ETHYNYL-17-BETA-OL-3-ONE
Androst-4-en-3-one, 17alpha-ethynyl-17-hydroxy-
Pregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-
17alpha-Ethynyl-17beta-hydroxyandrost-4-en-3-one
17-beta-Hydroxy-17-alpha-ethynyl-4-androsten-3-one
17α-Ethynyltestosterone, 17β-Hydroxy-4,17α-pregnen-20-yn-3-one, 4,17α-Pregnen-17β-ol-20-yn-3-one
(8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHY
Ethisterone,17α-Ethynyltestosterone, 17β-Hydroxy-4,17α-pregnen-20-yn-3-one, 4,17α-Pregnen-17β-ol-20-yn-3-one
(8R,9S,10R,13S,14S,17S)-17-ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
(8R,9S,10R,13S,14S,17R)-17-ETHYNYL-17-HYDROXY-10,13-DIMETHYL-1,2,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE

CAS:

434-03-7

MF:

C21H28O2

MW:

312.45

EINECS:

207-096-5

Product Categories:

Steroids;
Acetylenes;
Biochemistry;
Functionalized Acetylenes;
Hydroxyketosteroids;
Intermediates & Fine Chemicals;
Metabolites & Impurities;
Inhibitors;
progestogen estrogen;
Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals;
Steroid and Hormone;
Pharmaceuticals

Mol File:

434-03-7.mol

 

Detailed

Ethisterone Chemical Properties

Melting point 

263-269 °C(lit.)

alpha 

D23 +23.8° (dioxane); D25 -32.0° (pyridine)

Boiling point 

392.36°C (rough estimate)

density 

1.0697 (rough estimate)

refractive index 

33 ° (C=1, Pyridine)

storage temp. 

-20°C Freezer

pka

13.10±0.60(Predicted)

form 

neat

Water Solubility 

soluble in chloroform, DMSO (0.05 mg/ml), acetone (slightly ), ethanol (<1 mg/ml at 25°C), and water (<1 mg/ml at 25°C).

Merck 

14,3741

BRN 

1889895

InChIKey

CHNXZKVNWQUJIB-CEGNMAFCSA-N

CAS DataBase Reference

434-03-7

NIST Chemistry Reference

Ethisterone(434-03-7)

 

Safety Information

Hazard Codes 

Xn,T

Risk Statements 

40-48-61

Safety Statements 

22-24/25-45-53

RIDADR 

UN 2811

WGK Germany 

3

RTECS

TU5570250

HS Code 

29372390

 

Ethisterone Usage And Synthesis

Chemical Properties

Off-White Powder

Originator

Lutocyclin,Ciba

Uses

Synthetic progestogen; metabolite of Danazol; intermediate in the synthesis of Spironolactone

Definition

ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 17beta hydrogen is replaced by an ethynyl group.
Ethisterone was the first orally active progestin and is a metabolite of danazol.

Manufacturing Process

0.5 part of δ5:6-17-ethinyl-androstendiol-(3:17) is dissolved in 10 parts of dry acetone, the solution is mixed with a solution of 1 part of tertiary aluminum butylate in 40 parts of absolute toluene and the whole is heated to boiling in a reflux apparatus for 21 hours.
After the reaction mixture has cooled it is diluted with 100 parts of ether, the solution is washed with dilute mineral acid and with water, dried and the solvent is evaporated. In this manner there is obtained δ5:6-17-ethinyl-androstene-3-one-17-ol (ethisterone); MP: 270°- 272°C; it may be recrystallized from ethyl acetate.

Therapeutic Function

Progestin

 

Ethisterone Preparation Products And Raw materials

Raw materials

Dehydroepiandrosterone

Boldenone, Oxymetholone, Drostanolone, Testosterone, Nandrolone, Trenbolone    

Designed by   HuishangMedia

Copyright © 2008-2022 J·S Biology Co.,LTD All Rights Reserved 

Design by Huishang Media

  • Online Consultation

    If you have any questions or ask for a quote, please submit your information here and we will respond to you immediately.