Melting point 

178-183 °C

alpha 

27 º

Boiling point 

372.52°C (rough estimate)

density 

1.0320 (rough estimate)

refractive index 

1.4709 (estimate)

Fp 

9℃

storage temp. 

Controlled Substance, -20°C Freezer

form 

neat

pka

15.08±0.60(Predicted)

Water Solubility 

344.3g/L(temperature not stated)

Merck 

13,8872

BRN 

2056371

InChIKey

NVKAWKQGWWIWPM-ABEVXSGRSA-N

CAS DataBase Reference

NIST Chemistry Reference

EPA Substance Registry System

Hazard Codes 

Risk Statements 

Safety Statements 

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

RTECS 

BV8052000

Description

Stanolone is well known as dihydrotestosterone (DHT), which is an endogenous androgen sex steroid and hormone.
It is an agonist of the androgen receptor (AR).
It plays important physiological role in sexual differentiation, maturation of the penis and scrotum, hair, sebum production and development and maintenance of the prostate gland and seminal vesicles.It is mainly used for the treatment of male hypogonadism, androgen deficiency of severe illness, androgen deficiency of ageing and microphallus in infancy.

Chemical Properties

White Crystalline Solid

Originator

Neodrol,Pfizer,US,1953

Uses

Anabolic steroid. Controlled substance

Definition

ChEBI: A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with alpha- configuration at position 5.

Manufacturing Process

A solution of 1.0 g of 3,17-androstandione in 50 ml of methanol and containing 1 g of selenium dioxide, was allowed to remain in an ice-chest overnight. The formed 3,3-dimethoxyandrostan-17-one was not separated. 1 g of solid potassium hydroxide and 2.5 g of sodium borohydride in 2.5 ml of water were added and the mixture allowed to react at room temperature for 24 hours.
The solution was then poured into a large excess of water, extracted with methylene chloride, the organic layer dried and evaporated to a residue.
The residue was dissolved in ether, and a small amount of selenium removed by filtration.
The ether was boiled off and the organic material dissolved in 100 ml of boiling acetone. 25 ml of diluted hydrochloric acid were added, the solution boiled for 5 minutes and then allowed to cool.
Upon crystallization, 0.85 g of androstan-17β-ol-3-one was obtained, melting point 175°C to 178°C.

Therapeutic Function

Androgen

References

https://en.wikipedia.org/wiki/Dihydrotestosterone#Medical_use
Swerdloff, R. S., and C. Wang. "Dihydrotestosterone: a rationale for its use as a non-aromatizable androgen replacement therapeutic agent."Baillieres Clin Endocrinol Metab 12.3(1998):501.