ANDARINE OVERVIEW INFORMATION

Andarine is an investigational drug that has not yet been approved by the US Food and Drug Administration (FDA). It is part of a class of drugs called selective androgen receptor modulators (SARMs). Some supplement companies have included andarine in products for bodybuilding. The FDA considers supplements containing andarine to be illegal.

People use andarine to improve athletic performance and for conditions such as involuntary weight loss in people who are very ill (cachexia or wasting syndrome), osteoporosis, and prostate health, but there is no good scientific evidence to support these uses. Using andarine can also be unsafe.

How does it work?

Andarine attaches to proteins in the body known as androgen receptors. When andarine binds to these receptors, it tells the muscles and bones in the body to grow. Unlike some other chemicals that bind to androgen receptors, such as steroids, andarine doesn't seem to cause as many side effects in other parts of the body.

ANDARINE USES & EFFECTIVENESS

Age-related muscle loss (sarcopenia).

Athletic performance.

Enlarged prostate (benign prostatic hyperplasia or BPH).

Involuntary weight loss in people who are very ill (cachexia or wasting syndrome).

Osteoporosis.

Prostate cancer.

Other conditions.

More evidence is needed to rate andarine for these uses.

ANDARINE SIDE EFFECTS & SAFETY

When taken by mouth: Andarine is POSSIBLY UNSAFE. Liver damage, heart attack, and stroke have been reported in some people taking drugs like andarine.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There isn't enough reliable information to know if andarine is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

ANDARINE DOSING

The appropriate dose of andarine depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for andarine. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

What are SARMs?

Selective Androgen Receptor Modulators (SARMs) are a class of therapeutic compounds that have similar anabolic properties to anabolic steroids, but with reduced androgenic (producing male characteristics) properties. As an example, the androgen receptor is activated by binding androgens, such as testosterone. Unlike anabolic steroids, which bind to androgen receptors in many tissues all over the body, individual SARMs selectively bind androgen receptors in certain tissues, but not in others. 

In medical settings, this could be very useful for stimulating specific tissue growth like muscle and bone, while avoiding unwanted side effects in other tissues like the liver or skin. SARMs are being evaluated as a clinical treatment for muscle-wasting caused by several diseases, such as osteoporosis, cancer, heart failure, chronic obstructive pulmonary disease, end-stage liver disease, end-stage renal disease, and HIV. To date, all SARMs are for investigational purposes only.

Are SARMs prohibited on the World Anti-Doping Agency (WADA) Prohibited List?

All SARMs are prohibited at all times (both in and out-of-competition) for all athletes, from those competing at the highest level of sport to those competing at the recreational level. SARMs are listed in the category of “Other Anabolic Agents” under section S1.2 of the WADA Prohibited List.

Examples of SARMs include: ostarine (Enobosarm, MK 2866), andarine, LGD-4033 (ligandrol), and RAD140.[3] SARMs have the potential to be misused for performance enhancement in sport due to their anabolic properties, as well as their ability to stimulate androgen receptors in muscle and bone, leading to bone and muscle growth.

ATTENTION: All these products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human and veterinary purposes.