Anecortave Acetate

Name	Anecortave Acetate
Synonyms	H6; Al 3789; Retaane; NSC 15475; NSC 24345; Anecortave; Anacorta acetate; anecortave acetate; ANECORTAVE ACETATE (200 MG)F0E2980.997MG/MG(AI); Pregna-4,9(11)-diene-17-ol-3,20-dione-21-acetate
CAS NO	7753-60-8
CBNumber	CB5501441
Molecular Formula	C23H29O6-
MOL File	7753-60-8.mol
Molecular Weight	401.47276

Anecortave Acetate Chemical Properties
Melting point	230-234°C
alpha	D +117° (c = 1.0 in CHCl3); D22 +124° (c = 1.04 in CHCl3)
density	1.23±0.1 g/cm3(Predicted)
pka	12.47±0.60(Predicted)
storage temp	-20?C Freezer

Anecortave Acetate Usage And Synthesis
Chemical Properties	Off-White Solid
Uses	As an angiostatic steroid, Anecortave Acetate can be used in treatment of macular degeneration.
Enzyme inhibitor	This novel angiogenesis pro-drug (FW = 386.48 g/mol; CAS 7753-60-8) is taken up and metabolically de-esterified to form the aqnecortave, a synthetic steroid that suppresses the development and elongation of neovascular sprouts and tip cell motility in a VEGF-treated retinal explant model in a dose-dependent manner. Whether used as monotherapy or in combination with sub-therapeutic doses of cisplatin, anecortave acetate significantly controlled tumor burden in a murine retinoblastoma model.

FAQ

MOQ: 100 gram

Pack material: Plastic bag + Shockproof film + shockproof envelope + Cartons.

Shipment: By express to buyers’ door. 100% make sure delivery.

Payment: TT/ Western Union/BTC/ETV/VISA and so on, please contact by email.

Shipment time: Within three working days after payment. Usually need ten days to arrive buyers’ address. Resend if lost.

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