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DNP (2,4-Dinitrophenol)
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DNP (2,4-Dinitrophenol)

DNP CAPSULE

GENERIC NAME(S): 2,4-Dinitrophenol

Name: DNP (2,4-Dinitrophenol)

Form: capsules

Dosage: 200mg/capsule

Package:  100capsules/bottle.

Inventory: 1000 bottles for sell.

MOQ: 10 bottles.

Pack material: Shockproof film, shockproof envelope, and Cartons.  

Logo:  with or without both ok. 

OEM:  Offer OEM service. Customed dosage & brand & LOGO & package. OEM MOQ is 100 bottles.

Shipment: By express to buyers’ door. 100% make sure delivery. 

Payment: TT/ Western Union/BTC/ETV/VISA and so on, please contact by email. 

Shipment time: Within three working days after payment. Usually need ten days to arrive buyer ‘s address. Resend if lost.


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Description

2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects. DNP is sold mostly over the internet under a number of different names as a weight loss/slimming aid. It causes uncoupling of oxidative phosphorylation; the classic symptom complex associated with toxicity of phenol-based products such as DNP is a combination of hyperthermia, tachycardia, diaphoresis and tachypnoea, eventually leading to death. Fatalities related to exposure to DNP have been reported since the turn of the twentieth century. To date, there have been 62 published deaths in the medical literature attributed to DNP. In this review, we will describe the pattern and pathophysiology of DNP toxicity and summarise the previous fatalities associated with exposure to DNP. Dnp 5 MG Tablet is used in the treatment of dementia associated with Alzheimer's disease. It is not recommended in patients with gastrointestinal bleeding and lung diseases. This medicine does not cure Alzheimer's disease; it improves the symptoms of the disease and delays disease progression.

The pharmacologic treatment of obesity has been challenging. Previously, amphetamine derivatives, such as dexflenfluramine, fenfluramine and phentermine, were used as centrally active appetite suppressants; however, their use is associated with valvular heart disease and the development of pulmonary hypertension. Sibutramine (Reductil™ Abbott Laboratories), a newer centrally active appetite suppressant and the lipase inhibitor orlistat (Xenical™, Roche) are currently being used as ‘diet pills’, but have unpleasant side effects. However, for the majority of individuals with morbid obesity (body mass index >35 kg/m2), obesity surgery (‘gastric banding’) is often the treatment modality of choice, particularly in those associated severe co-morbidities. Regular use of 2,4-dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant side effects.

The first death due to DNP (C6H4N2O5) was reported in 1918 and was secondary to occupational exposure. Currently marketing of DNP, which is predominately through the internet, is targeted towards primarily body builders who are attempting to lose fat but retain muscle bulk. Additionally, it is widely available on the internet and is marketed as a ‘safe weight loss’ drug. Individuals are able to purchase ‘large quantities’, such as kilograms of DNP powder or hundreds/thousands of DNP-containing tablets. There are many regimes for taking the drug, all of which rely on the metabolic stimulatory effects of the drug. It has a small therapeutic index and is extremely dangerous in overdose. In this review, we will summarise the pharmacology of DNP, the potential mechanisms for its toxicity and the clinical evidence of harm associated with the use of DNP.


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Side effects

Major & minor side effects 

Diarrhea

Loss of appetite

Nausea and Vomiting

Trouble sleeping

Dizziness

Frequent urination

Headache

Weight loss

Unusual bleeding

Join pain



Uses

What is it prescribed for?

Alzheimer's disease

This medicine is used in the treatment of Alzheimer's disease which is a progressive brain disorder characterized by memory loss and difficulty in thinking.



How long does it take for this medicine to take effect?

The amount of time required for this medicine to show its action is not clinically established.

How long do the effects of this medicine last?

The amount of time for which this medicine remains active in the body is not clinically established.

Is it safe to consume alcohol while taking this medicine?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?

No habit forming tendency has been reported

Can this medicine be taken during pregnancy?

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Can this medicine be taken while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.


If OVERDOSE is suspected

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.


Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.

  • Do not share your drugs with others and do not take anyone else's drugs.Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.

  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about nandrolone, please talk with your doctor, nurse, pharmacist, or other health care provider.

  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened


Warnings

PELIOSIS HEPATIS, A CONDITION IN WHICH LIVER AND SOMETIMES SPLENIC TISSUE IS REPLACED WITH BLOOD-FILLED CYSTS, HAS BEEN REPORTED IN PATIENTS RECEIVING ANDROGENIC ANABOLIC STEROID THERAPY. THESE CYSTS ARE SOMETIMES PRESENT WITH MINIMAL HEPATIC DYSFUNCTION, BUT AT OTHER TIMES THEY HAVE BEEN ASSOCIATED WITH LIVER FAILURE. THEY ARE OFTEN NOT RECOGNIZED UNTIL LIFE-THREATENING LIVER FAILURE OR INTRA-ABDOMINAL HEMORRHAGE DEVELOPS. WITHDRAWAL OF DRUG USUALLY RESULTS IN COMPLETE DISAPPEARANCE OF LESIONS. LIVER CELL TUMORS ARE ALSO REPORTED. MOST OFTEN THESE TUMORS ARE BENIGN AND ANDROGEN-DEPENDENT, BUT FATAL MALIGNANT TUMORS HAVE BEEN REPORTED. WITHDRAWAL OF DRUG OFTEN RESULTS IN REGRESSION OR CESSATION OF PROGRESSION OF THE TUMOR. HOWEVER, HEPATIC TUMORS ASSOCIATED WITH ANDROGENS OR ANABOLIC STEROIDS ARE MUCH MORE VASCULAR THAN OTHER HEPATIC TUMORS AND MAY BE SILENT UNTIL LIFE-THREATENING INTRA-ABDOMINAL HEMORRHAGE DEVELOPS. BLOOD LIPID CHANGES THAT ARE KNOWN TO BE ASSOCIATED WITH INCREASED RISK OF ATHEROSCLEROSIS ARE SEEN IN PATIENTS TREATED WITH ANDROGENS AND ANABOLIC STEROIDS. THESE CHANGES INCLUDE DECREASED HIGH-DENSITY LIPOPROTEIN AND SOMETIMES INCREASED LOW-DENSITY LIPOPROTEIN. THE CHANGES MAY BE VERY MARKED AND COULD HAVE A SERIOUS IMPACT ON THE RISK OF ATHEROSCLEROSIS AND CORONARY ARTERY DISEASE.


How do I store and/or throw out?

If you need to store it at home, talk with your doctor, nurse, or pharmacist about how to store it.

PROTECT FROM LIGHT. Store in carton until contents are used.


ATTENTION: All these products are strictly for LABORATORY AND RESEARCH PURPOSES ONLY. They are not to be used for any human and veterinary purposes.

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